GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs2076028 | 1 | rs5750627 | chr22:38982321 | TOMM22 | chr22:39077954-39080763:+ | -0.17 | -3.82 | 0.000149 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750630 | chr22:38985818 | JOSD1 | chr22:39081549-39096459:- | -0.16 | -4.24 | 2.72E-5 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750630 | chr22:38985818 | TOMM22 | chr22:39077954-39080763:+ | -0.2 | -4.3 | 2.08E-5 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750633 | chr22:38993467 | LOC646851 | chr22:38974125-39052634:- | 0.14 | 3.86 | 0.000131 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750633 | chr22:38993467 | TOMM22 | chr22:39077954-39080763:+ | -0.16 | -3.52 | 0.000471 | Resting heart rate |
| THCA | cis | rs17122021 | 1 | rs57506367 | chr11:118141993 | AMICA1 | chr11:118064442-118095809:- | 0.09 | 4.1 | 4.81E-5 | Pain |
| THCA | cis | rs17122021 | 1 | rs57506367 | chr11:118141993 | MPZL2 | chr11:118124135-118135009:- | 0.23 | 7.67 | 9.93E-14 | Pain |
| THCA | cis | rs17122021 | 1 | rs57506367 | chr11:118141993 | TREH | chr11:118528942-118550381:- | -0.17 | -3.37 | 0.000816 | Pain |
| THCA | cis | rs2076028 | 1 | rs5750649 | chr22:39036769 | LOC646851 | chr22:38974125-39052634:- | 0.13 | 3.54 | 0.000435 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750649 | chr22:39036769 | TOMM22 | chr22:39077954-39080763:+ | -0.17 | -3.67 | 0.000267 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750652 | chr22:39048316 | LOC646851 | chr22:38974125-39052634:- | 0.13 | 3.54 | 0.000435 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750652 | chr22:39048316 | TOMM22 | chr22:39077954-39080763:+ | -0.17 | -3.67 | 0.000267 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750659 | chr22:39068789 | JOSD1 | chr22:39081549-39096459:- | -0.15 | -3.86 | 0.000127 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750659 | chr22:39068789 | LOC646851 | chr22:38974125-39052634:- | 0.13 | 3.43 | 0.000646 | Resting heart rate |
| THCA | cis | rs2076028 | 1 | rs5750659 | chr22:39068789 | TOMM22 | chr22:39077954-39080763:+ | -0.16 | -3.49 | 0.000525 | Resting heart rate |